Treatment is now being performed by proper skin care, which consists of thorough hygiene and wound healing. Patches must not be attached to the skin, instead bandages must be fastened with elastic meshes.

It is important to keep in mind that the bandage does not stick to the wounds because it causes further damage to the skin around the wound. Different ointments are used, which are also used for wound cleansing (antiseptics) and vaseline gases (thin gases in vaseline).

For wound care in patients with bullous epidermolysis, special silicone netting has been shown to be the best. They are so-called Mepitel mesh. They are useful because they do not damage the surrounding skin, and another advantage is that they can be left on the wound for a few days.

There are a number of methods to protect the skin:
  • Maintaining a room at a suitable temperature to avoid body overheating
  • Using lubricants to keep the skin moist
  • Buying soft and simple clothes that is not difficult to put on
  • Wearing gloves during sleep to prevent scratching
  • In the treatment very important role, if not a key role, is proper diet that must be caloric and rich in proteins.
  • In addition, the food must usually be soft so it can be easily chewed, and in some cases it must be thin or minced.
    Also, a balanced diet in combination with the use of sterile care supplies is essential to prevent infections, as it strengthens the body and immunity.

    It is also important to take iron, vitamin and mineral minerals permanently.

    In the case of permanent malnutrition which can not be solved due to the weakness of the patient, a special "tube" is inserted into the abdominal wall of the stomach.

    Through this tube, the patient can be fed with special food overnight while sleeping via a special pump. This operation does not rule out further nutrition on the mouth.

    Prevention of stiff joints is done by regular physical therapy and the cleavage of all joints. Coalescence of the fingers on the hands and toes on feet must be surgically corrected.

    Such operations are temporary solution, because wounds continue to develop on the skin of the patient and lead to further coalescence of the fingers.

    Operative procedures, however, make it possible to use the hands for these patients and lead a "normal" life.

    After such corrective surgery it is important to wear special gloves made individually for each patient (taking the imprint), which prevent that is slow down the coalescence .

    Special creams are applied to the eyes that will protect the eyes from the onset of sores, while in cases where the esophagus is narrowed, it is necessary to extend it by special procedures.